This report is based on the analysis of official and media texts describing the national and regional developments of the COVID crisis and the role of volunteer work. We also refer to official statistics, surveys, and research literature available on the topic. Additionally, we have conducted interviews with NGO leaders and volunteer personnel by phone and face-to-face. The data cover the period ...

This project report discusses global drivers affecting the development of key industries in the European Arctic (EA). Aquaculture is important for littoral states in the North, forestry and mining for northern Scandinavia, and tourism throughout the northern regions in the EA, and all are affected by globalization. Globalization is not a homogeneous, uniform phenomenon, but consists of various global ...

Invasiveness is a hallmark of aggressive cancer like malignant melanoma, and factors involved in acquisition or maintenance of an invasive phenotype are attractive targets for therapy. We investigated melanoma phenotype modulation induced by the metastasis-promoting microenvironmental protein S100A4, focusing on the relationship between enhanced cellular motility, dedifferentiation and metabolic ...

<i>Background</i>: In precision cancer medicine, the challenge is to prioritize DNA driver events, account for resistance markers, and procure sufficient information for treatment that maintains patient safety. The MetAction project, exploring how tumor molecular vulnerabilities predict therapy response, first established the required workflow for DNA sequencing and data interpretation (2014–2015). ...

Denne rapporten inngår som en del av regjeringens <i>Kunnskapsinnhenting ‐ verdiskaping i nord</i>. En rekke sektorrapporter og rapporter med tverrgående tema er utarbeidet, men den samiske dimensjonen i fremtidig næringsutvikling ble i liten grad belyst gjennom disse studiene. Denne rapporten forsøker å gi et bilde av næringslivet i samiske områder og hvilke utviklingsmuligheter mht. verdiskaping ...

Most patients whose large bowel cancer has spread to other organs do not respond to immune therapy. We detected a rare gene mutation, termed 9p24.1 copy-number gain (CNG), in an otherwise incurable colorectal cancer that provoked an immune therapy response. We identified this gene mutation by gene-panel sequencing of DNA from a liver metastasis biopsy from a patient who had disease refractory to ...

Although clinical management of melanoma has changed considerably in recent years, intrinsic treatment resistance remains a severe problem and strategies to design personal treatment regimens are highly warranted. We have applied a three-dimensional (3D) <i>ex vivo</i> drug efficacy assay, exposing disaggregated cells from 38 freshly harvested melanoma lymph node metastases and 21 patient derived ...